The cancer research program consists of several laboratories with state-of-the- art equipment and core facilities in support of cancer research and anticancer drug discovery and development.
Active cancer research is focused on understanding the molecular mechanisms of cancer initiation, progression and metastasis, discovering new anticancer drugs through synthetic chemistry and natural sources, and developing innovative targeted cancer prevention and treatment strategies.
Dr. Levenson and Dr. Pezzuto are in charge of the cancer research program. You may contact Drs. Levenson or Pezzuto should you have an interest in cancer research and anticancer drug discovery.
Projects at the Center
Mechanisms of cancer progression and metastasis
Epigenetic mechanisms of cancer progression
Gene expression profiling and pathways identification
microRNAs in cancer
Pre-clinical mouse models: xenografts and transgenic mice
Natural bioactive molecules for anticancer drug development
Lead identification and development including computational chemistry modeling and structure-based design
Pharmacology and efficacy of anticancer drugs
Safety, drug metabolism and pharmacokinetics
Light Cycle 480 Real-time RT-PCR
Synergy Microplate Reader
Cytoflex Flow Cytometer
Microscope Imaging System
Mammalian Tissue Culture
Schrodinger Computational Drug Design Suite
Structural Biology Program Suites
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