New methodologies for carbon-boron bond formation to synthesize boron-containing unnatural amino acids for use in cancer therapy. Synthesis of chemical libraries of boron-containing agents for use in the treatment of brain cancer and neurodegenerative diseases. Development of chemical libraries of PET and SPECT imaging agents for non-invasive diagnoses of Alzheimer's disease and brain cancer. Development of new therapeutic and diagnostic agents for brain cancer, prostate cancer, obesity and cardiovascular diseases.
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